SCHEMBL29429182

SCHEMBL29429182

O=c1[nH]cnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2COP(=O)(O)O[C@H]2[C@@H](O)[C@H](n3cnc4c(=O)[nH]cnc43)O[C@@H]2CO)[C@@H](OP(=O)(O)O)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ P2RX3 P56373 1/20 0.69
▸ RNASEL Q05823 7/20 0.58
▸ ADORA1 P30542 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29736455 0.95 P2RX3 (0.77) P2RX3RNASEL
SCHEMBL18087247 0.87 P2RX3 (0.68) P2RX3RNASEL
SCHEMBL16727889 0.87 P2RX3 (0.68) P2RX3RNASEL
SCHEMBL22381588 0.84 RNASEL (0.66) RNASELADORA1
SCHEMBL29547343 0.84 RNASEL (0.65) RNASELADORA1
SCHEMBL18521787 0.84 RNASEL (0.77) RNASEL
SCHEMBL29452474 0.84 P2RX3 (0.65) P2RX3RNASELADORA1
SCHEMBL24160912 0.83 P2RX3 (0.85) P2RX3RNASELADORA1
SCHEMBL18258283 0.83 P2RX3 (0.85) P2RX3RNASELADORA1
SCHEMBL22399796 0.83 RNASEL (0.57) P2RX3RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024197401-A1 1,3,4-THIADIAZOL-2-YL CARBOXAMIDE AND 1,3-THIAZOL-2-YL CARBOXAMIDE COMPOUNDS AND USES THEREOF AS INHIBITORS OF HUMAN POLYMERASE THETA REPARE THERAPEUTICS INC. (CA) 2024-10-03 — — WO claimed
CN-109324141-B Characteristic fingerprint spectrum of guangdong or processed products thereof, and construction method and application thereof 广州白云山中药饮片有限公司 2022-05-03 — — CN claimed
WO-2026100273-A1 METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE NTT株式会社 2026-05-15 — — WO disclosed
US-20260022114-A1 N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (1,3-THIAZOLYL)](SUBSTITUTED)CARBOXAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING THE AMIDE COMPOUNDS AND OF THEIR USE GILEAD SCIENCES, INC. 2026-01-22 — — US disclosed
WO-2025226656-A1 HEPATITIS B VIRUS MRNA VACCINES MODERNATX, INC. (US) 2025-10-30 — — WO disclosed
EP-4594316-A1 N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (1,3-THIAZOLYL)](SUBSTITUTED)CARBOXAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING THE AMIDE COMPOUNDS AND OF THEIR USE Repare Therapeutics Inc. (CA) 2025-08-06 — — EP disclosed
CN-119811549-A Analysis method for relationship between process impurities and degradation impurities based on big data analysis technology 中国食品药品检定研究院 2025-04-11 — — CN disclosed
WO-2025064869-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER CIDARA THERAPEUTICS, INC. (US) 2025-03-27 — — WO disclosed
WO-2025064788-A2 CCR5 CONJUGATES AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-03-27 — — WO disclosed
US-12223181-B2 Storage device and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-02-11 — — US disclosed
EP-4459415-A2 OVERSHOOT-FREE FAST START-UP BANDGAP REFERENCE CIRCUIT, CHIP, AND ELECTRONIC DEVICE Vanchip (Tianjin) Technology Co. Ltd (CN) 2024-11-06 — — EP disclosed
EP-4114941-A2 IMPROVED METHODS AND COMPOSITIONS FOR MODULATING A GENOME Flagship Pioneering Innovations VI, LLC (US) 2023-01-11 — — EP disclosed
US-11485784-B2 Ranking system for immunogenic cancer-specific epitopes ACT GENOMICS (IP) CO., LTD. (HK) 2022-11-01 — — US disclosed
CN-112328000-B Ultra-low quiescent current quick response circuit and device 江苏清微智能科技有限公司 2022-08-26 — — CN disclosed
WO-2022153481-A1 POSTURE ESTIMATION APPARATUS, LEARNING MODEL GENERATION APPARATUS, METHOD, AND COMPUTER-READABLE RECORDINGMEDIUM NEC CORPORATION (JP) 2022-07-21 — — WO disclosed
CN-114566534-A High-voltage element of switching power supply circuit and manufacturing method thereof 立锜科技股份有限公司 2022-05-31 — — CN disclosed
US-20220157982-A1 HIGH VOLTAGE DEVICE OF SWITCHING POWER SUPPLY CIRCUIT AND MANUFACTURING METHOD THEREOF RICHTEK TECHNOLOGY CORPORATION (TW) 2022-05-19 — — US disclosed
CN-109324141-B Characteristic fingerprint spectrum of guangdong or processed products thereof, and construction method and application thereof 广州白云山中药饮片有限公司 2022-05-03 — — CN disclosed
CN-113985957-B Overshoot-free quick-start band gap reference circuit, chip and electronic equipment 唯捷创芯(天津)电子技术股份有限公司 2022-04-05 — — CN disclosed
CN-113985957-A Overshoot-free quick-start band gap reference circuit, chip and electronic equipment 唯捷创芯(天津)电子技术股份有限公司 2022-01-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022114-A1 N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (1,3-THIAZOLYL)](SUBSTITUTED)CARBOXAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING THE AMIDE COMPOUNDS AND OF THEIR USE POLK, POLQ, POLB P2RX3 3385/4885RNASEL 2277/4885ADORA1 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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