Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682179 | 1.00 | KMT2A (0.47) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL19601322 | 0.85 | KMT2A (0.45) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL17682197 | 0.83 | ADORA2B (0.60) | KMT2ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL30025066 | 0.83 | ADORA2B (0.60) | KMT2ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL29799179 | 0.82 | TRPA1 (0.47) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL17682244 | 0.82 | TRPA1 (0.47) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL17682175 | 0.82 | KMT2A (0.42) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL18819561 | 0.78 | KMT2A (0.41) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL17682220 | 0.76 | KMT2A (0.44) | KMT2ATRPA1POLBHIF1ALMNA | |
| SCHEMBL17682304 | 0.75 | KMT2A (0.54) | KMT2ATRPA1POLBHIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |
| EP-3205652-B1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG RAYNOVENT BIOTECH CO LTD (CN) | 2022-03-09 | — | — | EP | disclosed |