SCHEMBL2942999

SCHEMBL2942999

NCCCC[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 6/20 0.58
NPY1R P25929 3/20 0.56
NPY2R P49146 3/20 0.56
NPY4R P50391 3/20 0.56
UTS2R Q9UKP6 1/20 0.55
ERAP2 Q6P179 1/20 0.52
ERBB2 P04626 1/20 0.52
CCKBR P32239 4/20 0.51
ECE1 P42892 1/20 0.51
CCKAR P32238 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13933760 1.00 GHSR (0.58) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL2946041 0.94 ERAP2 (0.59) GHSRUTS2RERAP2ECE1
SCHEMBL16332701 0.91 ERAP2 (0.62) GHSRERAP2ECE1
SCHEMBL15391980 0.91 ERAP2 (0.62) GHSRERAP2ECE1
SCHEMBL30179257 0.90 ERAP2 (0.58) GHSRERAP2ECE1
SCHEMBL31202576 0.90 GHSR (0.66) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL30198541 0.89 ERAP2 (0.59) GHSRERAP2
SCHEMBL31211837 0.89 ERAP2 (0.59) GHSRUTS2RERAP2ECE1
SCHEMBL30688843 0.88 GHSR (0.65) GHSRUTS2R
SCHEMBL31666000 0.87 ERAP2 (0.58) GHSRNPY1RNPY2RNPY4RERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697401-B1 TETRAPEPTIDE REGULATING BLOOD GLUCOSE LEVEL IN DIABETES MELLITUS ACCESS BIOSCIENCE CJSC (RU) 2010-01-06 EP claimed
US-20070142298-A1 Tetrapeptide regulating blood glucose level in diabetes mellitus SANKT-PETERBURGSKAYA OBSCHESTVENNAYA ORGANIZATSIYA "SANKT-PETERBURGSKIY INSTITUT BIOREG (RU) 2007-06-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142298-A1 Tetrapeptide regulating blood glucose level in diabetes mellitus DNPEP, AADAT, ANPEP GHSR 364/4885NPY1R 202/4885NPY2R 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.