Sugi Predict

Sugi Predict / Compounds / SCHEMBL29430203

SCHEMBL29430203

SCHEMBL29430203

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)C(C)C)[C@@H](C)O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.61
▸ GCGR P47871 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880899 0.93 GLP1R (0.63) GLP1RGCGR
SCHEMBL29479876 0.89 GLP1R (0.70) GLP1R
SCHEMBL30433096 0.89 GLP1R (0.71) GLP1RGCGR
SCHEMBL30567781 0.87 GLP1R (0.66) GLP1RGCGR
SCHEMBL29742978 0.87 GLP1R (0.64) GLP1R
SCHEMBL30844082 0.87 OPRD1 (0.56) GLP1R
SCHEMBL31053729 0.86 GLP1R (0.57) GLP1R
SCHEMBL31094626 0.86 GLP1R (0.56) GLP1RGCGR
SCHEMBL31027924 0.85 GLP1R (0.60) GLP1RGCGR
SCHEMBL30512611 0.85 KISS1R (0.57) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220073636-A1 ANTIBODY POLYPEPTIDES THAT ANTAGONIZE CD40L DOMANTIS LIMITED (GB) 2022-03-10 — — US disclosed
Send feedback