SCHEMBL294322

SCHEMBL294322

CCCC[n+]1ccc(CO)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
MAPT P10636 3/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HTT P42858 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CHKA P35790 1/20 0.47
HSP90AA1 P07900 3/20 0.44
MAPK1 P28482 3/20 0.44
APAF1 O14727 2/20 0.44
RGS12 O14924 1/20 0.44
CHRM2 P08172 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300903 0.92 HTT (0.63) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL7319663 0.92 KMT2A (0.59) KMT2AMEN1MAPTTP53CYP1A2
SCHEMBL5306627 0.84 KMT2A (0.58) KMT2AMEN1MAPTTP53CYP1A2
Fluoride Ion SCHEMBL30330248 0.82 KMT2A (0.56) KMT2AMEN1MAPTTP53CYP1A2
Hydrochloric Acid SCHEMBL3044045 0.82 KMT2A (0.56) KMT2AMEN1MAPTTP53CYP1A2
SCHEMBL4895577 0.80 MEN1 (0.54) KMT2AMEN1MAPTTP53CYP1A2
SCHEMBL5290534 0.80 KMT2A (0.54) KMT2AMEN1MAPTTP53CYP1A2
SCHEMBL294241 0.79 CHKA (0.52) KMT2AMEN1MAPTTP53CYP1A2
SCHEMBL294104 0.79 LMNA (0.44) HTTSMN1; SMN2LMNAKDM4EHSP90AA1
Cetylpyridinium SCHEMBL5080744 0.79 KMT2A (0.68) KMT2AMEN1MAPTTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2276917-B1 DEVICE, SYSTEM AND METHOD FOR PROVIDING A REDUCING AGENT FOR A SYSTEM FOR THE SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES BOSCH GMBH ROBERT (DE) 2012-03-14 EP claimed
WO-2020031836-A1 POLYMERIZABLE IONIC LIQUID, POLYMER, CURABLE COMPOSITION, ELECTROCHEMICAL ELEMENT MATERIAL, AND ANTISTATIC MATERIAL セントラル硝子株式会社 2020-02-13 WO disclosed