Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433062 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL19926247 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| Hydrochloric Acid SCHEMBL28704545 | 0.98 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| Hydrochloric Acid SCHEMBL28698062 | 0.98 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| Hydrochloric Acid SCHEMBL29433049 | 0.98 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| Hydrochloric Acid SCHEMBL29433046 | 0.98 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL19925900 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL19925958 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL21116505 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL19926330 | 0.80 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075141-B | Opioid receptor \"bias\" ligand, preparation method and medical application thereof | 上海致根医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |