Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MECP2 | P51608 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846030 | 1.00 | MECP2 (0.51) | MECP2NPC1HPGDSMAP4K4MEN1 | |
| SCHEMBL3964365 | 0.86 | HPGDS (0.58) | HPGDSLTA4H | |
| SCHEMBL16159319 | 0.82 | HPGDS (0.55) | HPGDSLTA4H | |
| SCHEMBL2152660 | 0.79 | HPGDS (0.61) | HPGDSMAOALTA4H | |
| SCHEMBL5201307 | 0.78 | HPGDS (0.50) | HPGDSLTA4H | |
| SCHEMBL9510731 | 0.78 | NOTUM (0.54) | NPC1HPGDSMAP4K4LTA4HRAB9A | |
| SCHEMBL15883428 | 0.78 | NPC1 (0.51) | NPC1HPGDSMEN1LTA4HRAB9A | |
| SCHEMBL764967 | 0.78 | HPGDS (0.50) | HPGDSLTA4H | |
| SCHEMBL3098624 | 0.78 | RAB9A (0.51) | NPC1HPGDSLTA4HRAB9AKDM4E | |
| SCHEMBL18374809 | 0.78 | HPGDS (0.50) | HPGDSLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |