Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390027 | 1.00 | HTR2A (0.38) | HTR2ACYP2D6MAOAMAOBKDM4E | |
| SCHEMBL4393423 | 0.82 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL9817817 | 0.77 | MAOA (0.38) | HTR2ACYP2D6MAOAMAOBMEN1 | |
| SCHEMBL2006251 | 0.74 | HTR2A (0.42) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL16398711 | 0.74 | HTR2A (0.38) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL292481 | 0.74 | BRD4 (0.38) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL292479 | 0.74 | HTR2A (0.38) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL28793125 | 0.74 | HTR2A (0.34) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL9934350 | 0.74 | HTR2A (0.38) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL299075 | 0.72 | EDNRA (0.37) | HTR2ACYP2D6BRD4CCL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055766-A | Magic and non-magic serotonin receptor agonist and its preparing process and usage | 库莱恩有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117136050-A | Compositions and methods for treating neuronal disorders using cannabinoids | 因美制药公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115038786-A | Optimized tetrahydrocannabinolic acid (THCA) synthase polypeptides | 德美崔克斯公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-114729337-A | Optimized cannabinoid synthase polypeptides | 德美崔克斯公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3958856-A1 | COMPOSITIONS AND METHODS FOR USE OF CANNABINOIDS FOR NEUROPROTECTION | Inmed Pharmaceuticals Inc. (CA) | 2022-03-02 | — | — | EP | disclosed |
| CN-114007603-A | Compositions and methods for neuroprotection using cannabinoids | 因美制药公司 | 2022-02-01 | — | — | CN | disclosed |