Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4599403 | 1.00 | — | — | |
| Bicarbonate SCHEMBL16945860 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9511277 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28582066 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL25 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29061109 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL1331459 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331273 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2121875 | 0.94 | CA4 (0.67) | — | |
| Bicarbonate SCHEMBL714912 | 0.94 | CA4 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4530358-A2 | METHODS OF RELEASING AN EXTENDED CAPTURE PROBE FROM A SUBSTRATE AND USES OF THE SAME | 10x Genomics, Inc. (US) | 2025-04-02 | — | — | EP | disclosed |
| EP-4200441-B1 | METHODS OF RELEASING AN EXTENDED CAPTURE PROBE FROM A SUBSTRATE AND USES OF THE SAME | 10X GENOMICS INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20230220454-A1 | METHODS OF RELEASING AN EXTENDED CAPTURE PROBE FROM A SUBSTRATE AND USES OF THE SAME | 10X GENOMICS, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4200441-A1 | METHODS OF RELEASING AN EXTENDED CAPTURE PROBE FROM A SUBSTRATE AND USES OF THE SAME | 10X Genomics, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022060798-A1 | METHODS OF RELEASING AN EXTENDED CAPTURE PROBE FROM A SUBSTRATE AND USES OF THE SAME | 10X GENOMICS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |