Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24766554 | 1.00 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL17204101 | 0.73 | MAPT (0.61) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL24766072 | 0.72 | PIM1 (0.52) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL29434132 | 0.71 | PIM1 (0.49) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL24766055 | 0.71 | PIM1 (0.49) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL24766591 | 0.70 | CNR2 (0.46) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL24766572 | 0.70 | KMT2A (0.44) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL29434172 | 0.70 | KMT2A (0.44) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL913213 | 0.70 | KMT2A (0.63) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL24766035 | 0.69 | MAPT (0.43) | KMT2ACYP1A2CYP2D6MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022060996-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2022-03-24 | — | — | WO | disclosed |