Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434159 | 0.90 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL971891 | 0.90 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL29434160 | 0.90 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL29762483 | 0.87 | MAPT (0.61) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL245771 | 0.87 | MAPT (0.61) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL23299977 | 0.87 | MAPT (0.53) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL913213 | 0.87 | KMT2A (0.63) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL29434148 | 0.84 | CYP1A2 (0.50) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL24766463 | 0.84 | CYP1A2 (0.50) | MAPTCYP1A2CYP2D6KMT2ARAB9A | |
| SCHEMBL856718 | 0.83 | MAPT (0.61) | MAPTCYP1A2CYP2D6KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766874-B2 | Manufacturing process for triazine, pyrimidine and pyridine derivatives | UNIVERSITAET BASEL (CH) | 2020-09-08 | — | — | US | disclosed |
| US-10766874-B2 | Manufacturing process for triazine, pyrimidine and pyridine derivatives | UNIVERSITAET BASEL (CH) | 2020-09-08 | — | — | US | disclosed |
| US-20190016698-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | TORQUR AG (CH) | 2019-01-17 | — | — | US | disclosed |
| US-20190016698-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | TORQUR AG (CH) | 2019-01-17 | — | — | US | disclosed |
| EP-3134388-B1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | UNIV BASEL (CH) | 2019-01-09 | — | — | EP | disclosed |
| EP-3134388-B1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | UNIV BASEL (CH) | 2019-01-09 | — | — | EP | disclosed |
| US-10100031-B2 | Manufacturing process for triazine, pyrimidine and pyridine derivatives | UNIVERSITAET BASEL (CH) | 2018-10-16 | — | — | US | disclosed |
| EP-3134388-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | Universität Basel (CH) | 2017-03-01 | — | — | EP | disclosed |
| US-20170037027-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | TORQUR AG (CH) | 2017-02-09 | — | — | US | disclosed |
| US-20170037027-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | TORQUR AG (CH) | 2017-02-09 | — | — | US | disclosed |
| US-20170037027-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | TORQUR AG (CH) | 2017-02-09 | — | — | US | disclosed |
| WO-2015162187-A1 | DEWATERING OF SLUDGE | SOLENIS TECHNOLOGIES CAYMAN LP (CH) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162084-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | UNIVERSITAET BASEL (CH) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162084-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | UNIVERSITAET BASEL (CH) | 2015-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016698-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | IL5, WIZ, TPMT | MAPT 2285/4885CYP1A2 368/4885CYP2D6 208/4885 |
| US-10100031-B2 | Manufacturing process for triazine, pyrimidine and pyridine derivatives | IL5, WIZ, TPMT | MAPT 2255/4885CYP1A2 382/4885CYP2D6 222/4885 |
| US-20170037027-A1 | NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES | IL5, WIZ, TPMT | MAPT 2649/4885CYP1A2 318/4885CYP2D6 200/4885 |
| US-10766874-B2 | Manufacturing process for triazine, pyrimidine and pyridine derivatives | IL5, WIZ, TPMT | MAPT 2518/4885CYP1A2 468/4885CYP2D6 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.