Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24766463 | 1.00 | CYP1A2 (0.50) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL17204101 | 0.84 | MAPT (0.61) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL23299977 | 0.80 | MAPT (0.53) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL29434159 | 0.80 | MAPT (0.65) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL29434160 | 0.80 | MAPT (0.65) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL971891 | 0.80 | MAPT (0.65) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL24766582 | 0.79 | SMG1 (0.48) | CYP1A2MAPTKDM4ELMNATDP1 | |
| SCHEMBL29434171 | 0.79 | SMG1 (0.48) | CYP1A2MAPTKDM4ELMNATDP1 | |
| SCHEMBL913213 | 0.77 | KMT2A (0.63) | CYP1A2MAPTCYP2D6KMT2AMEN1 | |
| SCHEMBL245771 | 0.77 | MAPT (0.61) | CYP1A2MAPTCYP2D6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022060996-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2022-03-24 | — | — | WO | disclosed |