SCHEMBL29434542

CC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(N)=O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(C)C

nearest known ligand 0.68

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	6/20	0.68

▸	NMUR2	Q9GZQ4	5/20	0.63

▸	NMUR1	Q9HB89	5/20	0.63

▸	KDM1A	O60341	2/20	0.61

▸	KISS1R	Q969F8	2/20	0.60

▸	EP300	Q09472	1/20	0.60

▸	HIF1A	Q16665	1/20	0.60

▸	IL23R	Q5VWK5	1/20	0.59

▸	RAMP3	O60896	1/20	0.59

▸	CALCR	P30988	1/20	0.59

▸	NPY2R	P49146	1/20	0.59

▸	NPY4R	P50391	1/20	0.59

▸	NPY5R	Q15761	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17722481	0.90	TFPI (0.66)	TFPIKDM1ARAMP3CALCRNPY2R
SCHEMBL31072603	0.89	TFPI (0.72)	TFPINMUR2NMUR1KDM1ARAMP3
SCHEMBL17722478	0.89	TFPI (0.64)	TFPINMUR2NMUR1
SCHEMBL30137653	0.89	TFPI (0.69)	TFPINMUR2NMUR1KDM1A
SCHEMBL29404705	0.88	RAMP3 (0.70)	TFPINMUR2NMUR1RAMP3CALCR
SCHEMBL17722477	0.88	TFPI (0.63)	TFPINMUR2NMUR1RAMP3CALCR
SCHEMBL26454508	0.88	TFPI (0.63)	TFPINMUR2NMUR1KDM1ANPY2R
SCHEMBL26454697	0.88	TFPI (0.63)	TFPINMUR2NMUR1KDM1ARAMP3
SCHEMBL13086158	0.88	NMUR2 (0.64)	TFPINMUR2NMUR1
SCHEMBL17722507	0.88	TFPI (0.65)	TFPINMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11261237-B2	Modified pigment epithelium-derived factor (PEDF) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection	NORTHWESTERN UNIVERSITY (US)	2022-03-01	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11261237-B2	Modified pigment epithelium-derived factor (PEDF) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection	VEGFA, LITAF, FIBP	TFPI 607/4885NMUR2 2265/4885NMUR1 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.