SCHEMBL29404705

SCHEMBL29404705

CC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 5/20 0.70
▸ CALCR P30988 5/20 0.70
▸ TFPI P10646 6/20 0.67
▸ NPY2R P49146 7/20 0.64
▸ NPY4R P50391 7/20 0.64
▸ NPY5R Q15761 7/20 0.64
▸ NPY1R P25929 5/20 0.64
▸ NMUR2 Q9GZQ4 1/20 0.61
▸ NMUR1 Q9HB89 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405698 0.91 TFPI (0.70) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL30541676 0.89 TFPI (0.68) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL31072603 0.89 TFPI (0.72) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL30495834 0.89 RAMP3 (0.68) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL26454697 0.89 TFPI (0.63) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL30818417 0.89 TFPI (0.68) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL29434542 0.88 TFPI (0.68) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL30640886 0.88 RAMP3 (0.63) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL17722481 0.88 TFPI (0.66) RAMP3CALCRTFPINPY2RNPY4R
SCHEMBL26454508 0.88 TFPI (0.63) TFPINPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20250290128-A1 METHOD OF MEASURING MICROSATELLITE LENGTH VARIATIONS COLD SPRING HARBOR LABORATORY (US) 2025-09-18 — — US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 — — US disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
US-20240352431-A1 Variant Cytochrome P450 Monooxygenases and Uses Thereof BluumBio Inc. (US) 2024-10-24 — — US disclosed
WO-2024220320-A1 VARIANT CYTOCHROME P450 MONOOXYGENASES AND USES THEREOF BLUUMBIO, INC. (US) 2024-10-24 — — WO disclosed
CN-114126619-B Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2024-03-15 — — CN disclosed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 — — US disclosed
EP-4146629-A1 DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS The Feinstein Institutes for Medical Research (US) 2023-03-15 — — EP disclosed
CN-115515937-A Dimers for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-12-23 — — CN disclosed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 — — US disclosed
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-29 — — US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 — — US disclosed
US-11414405-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-08-16 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM RAMP3 1895/4885CALCR 1359/4885TFPI 2710/4885
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC RAMP3 803/4885CALCR 1707/4885TFPI 1882/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS RAMP3 965/4885CALCR 2542/4885TFPI 2300/4885
US-11414405-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM RAMP3 1895/4885CALCR 1359/4885TFPI 2710/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 RAMP3 1293/4885CALCR 1358/4885TFPI 3459/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 RAMP3 737/4885CALCR 1795/4885TFPI 1686/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC RAMP3 803/4885CALCR 1707/4885TFPI 1882/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM RAMP3 1895/4885CALCR 1359/4885TFPI 2710/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT RAMP3 1187/4885CALCR 1581/4885TFPI 2392/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR RAMP3 410/4885CALCR 118/4885TFPI 1309/4885
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC RAMP3 803/4885CALCR 1707/4885TFPI 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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