SCHEMBL29434673

SCHEMBL29434673

C=C(C)c1ccccc1[Si](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.32
PAX8 Q06710 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23493389 1.00 ADRA2A (0.38) ADRA2AADRA2BADRA2CIRAK4PAX8
SCHEMBL21829191 0.87 IRAK4 (0.33) ADRA2AADRA2BADRA2CIRAK4ALDH1A1
SCHEMBL9436594 0.84 ADRA2A (0.37) ADRA2AADRA2BADRA2CIRAK4PAX8
SCHEMBL9436640 0.84 ADRA2A (0.37) ADRA2AADRA2BADRA2CIRAK4PAX8
SCHEMBL29434563 0.84 ADRA2A (0.37) ADRA2AADRA2BADRA2CIRAK4PAX8
SCHEMBL6509782 0.79 ADRA2A (0.34) ADRA2AADRA2BADRA2CPAX8TSHR
SCHEMBL29434687 0.79 ADRA2A (0.34) ADRA2AADRA2BADRA2CPAX8TSHR
SCHEMBL30401462 0.78 ALDH1A1 (0.41) ADRA2AADRA2BADRA2CALDH1A1TSHR
SCHEMBL426113 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9436655 0.75 TSHR (0.36) ADRA2AADRA2BADRA2CPAX8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-20240425702-A1 Block Copolymer, Asphalt Composition, and Modified Asphalt Mixture ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
CN-114341206-B Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2024-12-20 CN disclosed
CN-115298225-B Hydrogenated conjugated diene polymer, hydrogenated conjugated diene polymer composition, rubber composition, and method for producing hydrogenated conjugated diene polymer 旭化成株式会社 2024-12-13 CN disclosed
CN-115348975-B Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2024-10-22 CN disclosed
CN-118546322-A Block copolymer, asphalt composition, and modified asphalt mixture 旭化成株式会社 2024-08-27 CN disclosed
CN-114174350-B Conjugated diene polymer, process for producing the same, oil-extended conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2024-04-30 CN disclosed
CN-112940364-B Conjugated diene polymer composition and tire 旭化成株式会社 2023-10-03 CN disclosed
CN-113493542-B Conjugated diene polymer, process for producing the same, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2023-09-22 CN disclosed
CN-113493543-B Conjugated diene polymer, process for producing the same, and rubber composition 旭化成株式会社 2023-09-05 CN disclosed
CN-113372630-B Conjugated diene polymer composition and tire 旭化成株式会社 2023-05-26 CN disclosed
WO-2023074089-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE 旭化成株式会社 2023-05-04 WO disclosed
CN-111936536-B Conjugated diene polymer, branching agent, method for producing conjugated diene polymer, oil-extended conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2023-04-07 CN disclosed
CN-115348975-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2022-11-15 CN disclosed
CN-115298225-A Hydrogenated conjugated diene polymer, hydrogenated conjugated diene polymer composition, rubber composition, and method for producing hydrogenated conjugated diene polymer 旭化成株式会社 2022-11-04 CN disclosed
CN-114341206-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2022-04-12 CN disclosed
CN-114174350-A Conjugated diene polymer, branching agent, method for producing conjugated diene polymer, oil-extended conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2022-03-11 CN disclosed