Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 9/20 | 0.87 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.87 |
| ▸ | MEN1 | O00255 | 5/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.87 |
| ▸ | POLB | P06746 | 1/20 | 0.87 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259468 | 1.00 | KCNK3 (0.87) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL12922066 | 0.94 | KCNK3 (0.77) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL4253897 | 0.91 | KCNK3 (0.93) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL10090678 | 0.90 | KMT2A (0.72) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL8461683 | 0.90 | MEN1 (0.73) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL259706 | 0.89 | MEN1 (0.77) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL259666 | 0.89 | KCNK3 (0.87) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL30608967 | 0.89 | KCNK3 (0.87) | KCNK3KCNK9MEN1KMT2APOLB | |
| SCHEMBL2908619 | 0.89 | MEN1 (0.89) | KCNK3KCNK9MEN1KMT2APOLB | |
| Dimethylamine SCHEMBL9292692 | 0.87 | MEN1 (0.69) | KCNK3KCNK9MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580404-A2 | SULFONAMIDE APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| CN-118126043-B | PLK4 inhibitor with high selectivity and preparation method and application thereof | 沈阳药科大学 | 2025-01-28 | — | — | CN | claimed |
| WO-2024114574-A1 | HIGH-SELECTIVITY PLK4 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2024-06-06 | — | — | WO | claimed |
| CN-118126043-A | PLK4 inhibitor with high selectivity and preparation method and application thereof | 沈阳药科大学 | 2024-06-04 | — | — | CN | claimed |
| EP-4140991-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2024-05-15 | — | — | EP | claimed |
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | claimed |
| WO-2024050041-A2 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE (US) | 2024-03-07 | — | — | WO | claimed |
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-118126043-B | PLK4 inhibitor with high selectivity and preparation method and application thereof | 沈阳药科大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-117466799-B | N-substituted phthalic acid diamide preparation method of imine compound | 西北师范大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-118420484-B | Method for preparing amide compounds | 四川大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118420484-A | Method for preparing amide compounds | 四川大学 | 2024-08-02 | — | — | CN | disclosed |
| WO-2024114574-A1 | HIGH-SELECTIVITY PLK4 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2024-06-06 | — | — | WO | disclosed |
| CN-118126043-A | PLK4 inhibitor with high selectivity and preparation method and application thereof | 沈阳药科大学 | 2024-06-04 | — | — | CN | disclosed |
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-114276270-A | Synthesis method of compound with amido bond | 湖北文理学院 | 2022-04-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | KCNK3 3991/4885KCNK9 3433/4885MEN1 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.