SCHEMBL259706

SCHEMBL259706

Cc1ccc(C(=O)Nc2cccc(C)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
RXFP1 Q9HBX9 1/20 0.77
RAB9A P51151 6/20 0.74
NPC1 O15118 5/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
TP53 P04637 1/20 0.74
NFKB1 P19838 1/20 0.74
NFKB2 Q00653 1/20 0.74
RELA Q04206 1/20 0.74
KCNK3 O14649 7/20 0.72
KCNK9 Q9NPC2 3/20 0.72
KCNH2 Q12809 1/20 0.72
POLB P06746 1/20 0.71
ALDH1A1 P00352 2/20 0.68
LMNA P02545 1/20 0.68
TSHR P16473 1/20 0.67
HSD17B10 Q99714 1/20 0.62
HTT P42858 2/20 0.62
MAPT P10636 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228168 0.93 RAB9A (0.71) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL8461683 0.90 MEN1 (0.73) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL14363224 0.90 MEN1 (0.73) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL29434800 0.89 KCNK3 (0.87) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL259468 0.89 KCNK3 (0.87) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL2908619 0.89 MEN1 (0.89) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL7234095 0.88 MEN1 (0.71) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL21620313 0.88 MEN1 (0.78) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL21133083 0.88 KCNK3 (0.86) MEN1KMT2ARXFP1RAB9ANPC1
SCHEMBL682877 0.88 MEN1 (0.71) MEN1KMT2ARXFP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
US-20220017762-A1 INK JET INK FOR FORMING AN INFRARED ABSORBING IMAGE, INFRARED ABSORBING IMAGE FORMING METHOD, AND RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2022-01-20 US disclosed
EP-3822253-A1 METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) 2021-05-19 EP disclosed
US-20210036294-A1 SEPARATION MEMBRANE COMPRISING COATING LAYER, METHOD OF PREPARING SAME, AND BATTERY USING SAME SAMSUNG SDI CO LTD (KR) 2021-02-04 US disclosed
US-20200347252-A1 INK COMPOSITION FOR INK JET PRINTING, IMAGE FORMING METHOD, AND RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2020-11-05 US disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed
EP-1402876-B1 Cosmetic composition containing fibers OREAL (FR) 2009-05-27 EP disclosed
US-20090126128-A1 Disazo Acid Dyes CLARIANT FINANCE (BVI) LIMITED (VG) 2009-05-21 US disclosed
US-20090126128-A1 Disazo Acid Dyes CLARIANT FINANCE (BVI) LIMITED (VG) 2009-05-21 US disclosed
US-20070037805-A1 Fused heteroaryl derivatives HAYAKAWA MASAHIKO 2007-02-15 US disclosed
US-20070037805-A1 Fused heteroaryl derivatives HAYAKAWA MASAHIKO 2007-02-15 US disclosed
US-7173029-B2 Fused heteroaryl derivatives ASTELLAS PHARMA INC. (JP) 2007-02-06 US disclosed
US-7173029-B2 Fused heteroaryl derivatives ASTELLAS PHARMA INC. (JP) 2007-02-06 US disclosed
US-7157548-B2 Crosslinked sulfonated polyimide films HANYANG HAK WON CO., LTD. (KR) 2007-01-02 US disclosed
US-7157548-B2 Crosslinked sulfonated polyimide films HANYANG HAK WON CO., LTD. (KR) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037805-A1 Fused heteroaryl derivatives PIK3CD, PIK3R3, PIK3C2A MEN1 3330/4885KMT2A 1722/4885RXFP1 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.