Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299696 | 1.00 | MEP1B (0.47) | MEP1BKMT2AENPP3CA1CA2 | |
| Hydrochloric Acid SCHEMBL5472661 | 0.98 | MEP1B (0.46) | MEP1BKMT2AENPP3CA1CA2 | |
| SCHEMBL1727450 | 0.83 | PDIA6 (0.51) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL29913439 | 0.83 | PDIA6 (0.51) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL4012814 | 0.81 | MEP1B (0.49) | MEP1BKMT2AMCL1ALDH1A1HTT | |
| SCHEMBL8404318 | 0.80 | CA12 (0.50) | KMT2AENPP3CA1CA2CA12 | |
| SCHEMBL8404311 | 0.80 | CA12 (0.50) | KMT2AENPP3CA1CA2CA12 | |
| SCHEMBL6766551 | 0.79 | MEP1B (0.51) | MEP1BKMT2AMCL1KDM4EALDH1A1 | |
| SCHEMBL533075 | 0.79 | KMT2A (0.51) | MEP1BKMT2AMCL1KDM4EALDH1A1 | |
| SCHEMBL31674581 | 0.79 | KMT2A (0.51) | MEP1BKMT2AMCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174266-A | Arylsulfonamide derivatives as MGLUR4 negative allosteric modulators | 豪夫迈·罗氏有限公司 | 2022-03-11 | — | — | CN | disclosed |