Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15117438 | 1.00 | KMT2A (0.48) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL15117439 | 1.00 | KMT2A (0.48) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL5533503 | 0.81 | KMT2A (0.43) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL693882 | 0.81 | KMT2A (0.43) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL693883 | 0.81 | KMT2A (0.43) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL15695372 | 0.77 | ALDH1A1 (0.40) | KMT2ARAB9AMAPK1MAPTNPC1 | |
| SCHEMBL28267692 | 0.75 | KMT2A (0.44) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL32680256 | 0.73 | KMT2A (0.40) | KMT2ARAB9AMAPK1MAPTPOLB | |
| SCHEMBL14459429 | 0.72 | HTR3E (0.42) | KMT2ARAB9AMAPTPOLBHTR3E | |
| SCHEMBL21030570 | 0.72 | MAPT (0.40) | KMT2ARAB9AMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761820-B | Chemical synthesis method of 3',4',5 '-trifluoro- [1,1' -biphenyl ] -2-amine | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |