SCHEMBL29435259

SCHEMBL29435259

Nc1nc(Oc2ccccc2OCc2ccccc2)c(Cl)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.46
MAPK14 Q16539 1/20 0.46
DCPS Q96C86 2/20 0.45
STAT3 P40763 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM1A O60341 2/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
RHEB Q15382 1/20 0.41
DHFR P00374 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ATP4A P20648 1/20 0.40
ATP4B P51164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19641833 1.00 LTA4H (0.46) LTA4HMAPK14DCPSSTAT3HTT
SCHEMBL19655811 0.86 HTT (0.49) STAT3HTTSMN1; SMN2KDM1AMAPT
SCHEMBL21001137 0.81 DHPS (0.51)
SCHEMBL29435282 0.79 PLAU (0.38) STAT3HTTSMN1; SMN2KDM1AMAPT
SCHEMBL19641832 0.79 PLAU (0.38) STAT3HTTSMN1; SMN2KDM1AMAPT
SCHEMBL21032979 0.77 TSHR (0.44) SMN1; SMN2MAPTLMNANPC1RAB9A
SCHEMBL19641805 0.75 PTGER1 (0.46) SMN1; SMN2MAPTPOLBNPC1
SCHEMBL19655849 0.74 PPIA (0.40) SMN1; SMN2NPC1RAB9A
SCHEMBL31442635 0.73 MGAM (0.47) LTA4HMAPK14SMN1; SMN2KDM1ARHEB
SCHEMBL810931 0.73 MGAM (0.47) LTA4HMAPK14SMN1; SMN2KDM1ARHEB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249710-B Herbicidal uracil pyridines 巴斯夫欧洲公司 2024-07-23 CN disclosed
CN-114249710-A Herbicidal uracils 巴斯夫欧洲公司 2022-03-29 CN disclosed
CN-109311842-B Herbicidal uracils 巴斯夫欧洲公司 2022-03-25 CN disclosed