SCHEMBL29435264

SCHEMBL29435264

CCOC(=O)CCOc1nc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.36
TNF P01375 6/20 0.36
PPOX P50336 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
PLA2G7 Q13093 1/20 0.33
POLB P06746 1/20 0.33
DHODH Q02127 2/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
LMNA P02545 2/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
FPR1 P21462 1/20 0.32
BAZ2B Q9UIF8 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28991747 0.91 PPOX (0.40) KAT2BPPOXL3MBTL1PLA2G7POLB
SCHEMBL29190282 0.86 DHODH (0.31) DHODH
SCHEMBL19641776 0.83 PPOX (0.39) PPOXL3MBTL1PLA2G7POLBKMT2A
SCHEMBL31291100 0.83 PPOX (0.39) PPOXL3MBTL1PLA2G7POLBKMT2A
SCHEMBL7594681 0.83 HRH4 (0.36) L3MBTL1
SCHEMBL22361943 0.82 PPOX (0.38) PPOXL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL7607651 0.81 GAA (0.37) L3MBTL1POLBMEN1KMT2AKDM4E
SCHEMBL31625521 0.81 PPOX (0.36) PPOXL3MBTL1PLA2G7DHODHMEN1
SCHEMBL19641827 0.81 PPOX (0.36) PPOXL3MBTL1PLA2G7DHODHMEN1
SCHEMBL22361942 0.80 PPOX (0.35) PPOXPLA2G7DHODHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249710-B Herbicidal uracil pyridines 巴斯夫欧洲公司 2024-07-23 CN disclosed
CN-114249710-A Herbicidal uracils 巴斯夫欧洲公司 2022-03-29 CN disclosed
CN-109311842-B Herbicidal uracils 巴斯夫欧洲公司 2022-03-25 CN disclosed