Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | PKM | P14618 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17992491 | 1.00 | BRD4 (0.80) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL17992497 | 0.89 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL19764638 | 0.86 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL29437293 | 0.86 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL29437328 | 0.85 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL19764643 | 0.85 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL9450615 | 0.85 | BRD4 (0.73) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL17992500 | 0.84 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL17992507 | 0.84 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL29437266 | 0.84 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662226-B | 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound | 中国科学院广州生物医药与健康研究院 | 2022-03-18 | — | — | CN | disclosed |