Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121313 | 1.00 | CYP2D6 (0.48) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL30970238 | 0.84 | CYP2D6 (0.63) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL29700592 | 0.82 | KCNH2 (0.44) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL23120736 | 0.82 | KCNH2 (0.44) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL30613519 | 0.81 | CYP2D6 (0.46) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL26127203 | 0.81 | CYP2D6 (0.46) | CYP2D6TSHRCYP2C19HIF1AKCNH2 | |
| SCHEMBL25243253 | 0.80 | KCNH2 (0.41) | KCNH2FPR2AKR1B1 | |
| SCHEMBL23121185 | 0.80 | KCNH2 (0.45) | TSHRKCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL29437918 | 0.80 | KCNH2 (0.45) | TSHRKCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL31434507 | 0.79 | TRAP1 (0.43) | KCNH2AKR1B1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568682-A | Novel compounds for the treatment of angiotensin II related diseases | 维科尔药物公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4208460-A1 | NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II | Vicore Pharma AB (SE) | 2023-07-12 | — | — | EP | disclosed |
| EP-4031240-A1 | NEW COMPOUNDS | Vicore Pharma AB (SE) | 2022-07-27 | — | — | EP | disclosed |
| CN-114786774-A | Novel compounds | 维科尔药物公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2022049372-A1 | NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II | VICORE PHARMA AB (SE) | 2022-03-10 | — | — | WO | disclosed |