Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120736 | 1.00 | KCNH2 (0.44) | KCNH2AKR1B1LMNAL3MBTL1GRIN2B | |
| SCHEMBL25243253 | 0.95 | KCNH2 (0.41) | KCNH2AKR1B1LMNAL3MBTL1GRIN2B | |
| SCHEMBL26127719 | 0.85 | L3MBTL1 (0.43) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL29437918 | 0.83 | KCNH2 (0.45) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL23121185 | 0.83 | KCNH2 (0.45) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL31434507 | 0.82 | TRAP1 (0.43) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL27535901 | 0.82 | LMNA (0.48) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL23121313 | 0.82 | CYP2D6 (0.48) | KCNH2AKR1B1HSP90B1TRAP1 | |
| SCHEMBL29047335 | 0.82 | KCNH2 (0.45) | KCNH2AKR1B1TLR7HSP90B1TRAP1 | |
| SCHEMBL29437923 | 0.82 | CYP2D6 (0.48) | KCNH2AKR1B1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031240-A1 | NEW COMPOUNDS | Vicore Pharma AB (SE) | 2022-07-27 | — | — | EP | disclosed |
| CN-114786774-A | Novel compounds | 维科尔药物公司 | 2022-07-22 | — | — | CN | disclosed |