Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MYLK | Q15746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.57 |
| ▸ | GMNN | O75496 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138090 | 1.00 | KMT2A (0.75) | KMT2AATMCYP3A4NFKB1CYP1A2 | |
| SCHEMBL31033068 | 0.99 | KMT2A (0.77) | KMT2AATMCYP3A4NFKB1CYP1A2 | |
| SCHEMBL5650140 | 0.99 | KMT2A (0.77) | KMT2AATMCYP3A4NFKB1CYP1A2 | |
| SCHEMBL29437927 | 0.89 | KMT2A (0.88) | KMT2AATMCYP1A2MEN1CYP2C19 | |
| SCHEMBL25531 | 0.89 | KMT2A (0.88) | KMT2AATMCYP1A2MEN1CYP2C19 | |
| SCHEMBL15934204 | 0.83 | KMT2A (0.79) | KMT2AATMCYP1A2MEN1LMNA | |
| SCHEMBL14256516 | 0.81 | KMT2A (0.75) | KMT2AATMCYP1A2MEN1CYP2C19 | |
| SCHEMBL12604576 | 0.81 | KMT2A (0.75) | KMT2AATMCYP1A2MEN1CYP2C19 | |
| SCHEMBL29678142 | 0.81 | KMT2A (0.70) | KMT2AATMCYP1A2CYP2C19HIF1A | |
| SCHEMBL32677285 | 0.80 | KMT2A (0.74) | KMT2AATMCYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180369428-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) | 2018-12-27 | — | — | US | claimed |
| EP-3281643-A2 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | Kyungpook National University Industry-Academic Cooperation Foundation (KR) | 2018-02-14 | — | — | EP | claimed |
| US-20200138982-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) | 2020-05-07 | — | — | US | disclosed |
| US-20200138982-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) | 2020-05-07 | — | — | US | disclosed |
| US-10583206-B2 | Radioactive probe for detecting hydrogen sulfide | Kyungpook National University Industry-Academic, Cooperation Foundation (KR) | 2020-03-10 | — | — | US | disclosed |
| US-20180369428-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) | 2018-12-27 | — | — | US | disclosed |
| EP-3281643-A2 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | Kyungpook National University Industry-Academic Cooperation Foundation (KR) | 2018-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369428-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | TST, CTH, CBS | KMT2A 4501/4885ATM 1485/4885CYP3A4 3262/4885 |
| US-20200138982-A1 | RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE | TST, SCLY, CTH | KMT2A 4261/4885ATM 1572/4885CYP3A4 3156/4885 |
| US-10583206-B2 | Radioactive probe for detecting hydrogen sulfide | TST, SCLY, CTH | KMT2A 4261/4885ATM 1572/4885CYP3A4 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.