Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 9/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875803 | 1.00 | MAPK1 (0.42) | MAPK1BRD4CREBBPP2RX7HPGDS | |
| SCHEMBL29965218 | 1.00 | MAPK1 (0.42) | MAPK1BRD4CREBBPP2RX7HPGDS | |
| SCHEMBL21875807 | 0.87 | MAPK1 (0.40) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL29438317 | 0.87 | MAPK1 (0.40) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL29965322 | 0.87 | MAPK1 (0.40) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL21875776 | 0.87 | MAPK1 (0.46) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL29964199 | 0.87 | MAPK1 (0.46) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL29438284 | 0.87 | MAPK1 (0.46) | MAPK1BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL21875780 | 0.87 | MAPK1 (0.40) | MAPK1BRD4CREBBPKMT2A | |
| SCHEMBL29438298 | 0.87 | MAPK1 (0.40) | MAPK1BRD4CREBBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064160-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (US) | 2022-03-03 | — | — | US | claimed |
| US-20220064160-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (US) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064160-A1 | BICYCLIC DERIVATIVES | FABP3, CYCS, PIGS | MAPK1 3920/4885BRD4 125/4885CREBBP 3338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.