SCHEMBL29438447

SCHEMBL29438447

O=C(O)CC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 3/20 0.43
▸ DPP8 Q6V1X1 2/20 0.43
▸ FAP Q12884 1/20 0.43
▸ DPP9 Q86TI2 1/20 0.43
▸ DPP7 Q9UHL4 1/20 0.43
▸ CMA1 P23946 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ACE P12821 2/20 0.40
▸ REN P00797 1/20 0.40
▸ ITGB1 P05556 1/20 0.38
▸ ITGA4 P13612 1/20 0.38
▸ FOLH1 Q04609 1/20 0.38
▸ RIMKLA Q8IXN7 1/20 0.38
▸ NAALAD2 Q9Y3Q0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574235 0.98 DPP4 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL15481300 0.91 DPP4 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL29706282 0.91 DPP4 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL7899891 0.89 GRB2 (0.41) DPP4DPP8FAPDPP9DPP7
SCHEMBL7899895 0.89 GRB2 (0.41) DPP4DPP8FAPDPP9DPP7
Hydrochloric Acid SCHEMBL7899918 0.89 GRB2 (0.41) DPP4DPP8FAPDPP9DPP7
Hydrochloric Acid SCHEMBL7899915 0.89 GRB2 (0.41) DPP4DPP8FAPDPP9DPP7
SCHEMBL29591671 0.88 GRB2 (0.44) DPP4DPP8FAPDPP9DPP7
SCHEMBL29630697 0.88 GRB2 (0.44) DPP4DPP8FAPDPP9DPP7
SCHEMBL29397117 0.87 DPP4 (0.46) DPP4DPP8FAPDPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136613-A1 COMPOSITIONS AND METHODS FOR TREATING OR AMELIORATING INFECTIONS San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation 2023-05-04 — — US claimed
US-20250228923-A1 COMBINED VACCINE AGAINST MYCOBACTERIUM TUBERCULOSIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-07-17 — — US disclosed
US-12318436-B2 Composition and method for spray drying an adjuvant vaccine emulsion ACCESS TO ADVANCED HEALTH INSTITUTE (US) 2025-06-03 — — US disclosed
US-12090198-B2 Combined vaccine against mycobacterium tuberculosis THE CHILDREN'S MEDICAL CENTER CORPORATION 2024-09-17 — — US disclosed
CN-116615436-A Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide 中国医学科学院药物研究所 2023-08-18 — — CN disclosed
US-20230136613-A1 COMPOSITIONS AND METHODS FOR TREATING OR AMELIORATING INFECTIONS San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation 2023-05-04 — — US disclosed
WO-2022170394-A1 RECOMBINANT STRAINS OF MYCOBACTERIUM BOVIS BCG JAMES COOK UNIVERSITY (AU) 2022-08-18 — — WO disclosed
US-20220249646-A1 COMPOSITION AND METHOD FOR SPRAY DRYING AN ADJUVANT VACCINE EMULSION ACCESS TO ADVANCED HEALTH INSTITUTE 2022-08-11 — — US disclosed
CN-114340665-A Compositions and methods for spray drying adjuvant vaccine emulsions 传染病研究所 2022-04-12 — — CN disclosed
EP-3976092-A1 COMPOSITION AND METHOD FOR SPRAY DRYING AN ADJUVANT VACCINE EMULSION Infectious Disease Research Institute (US) 2022-04-06 — — EP disclosed
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