Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438447 | 0.98 | DPP4 (0.43) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7899891 | 0.92 | GRB2 (0.41) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7899895 | 0.92 | GRB2 (0.41) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL7899918 | 0.91 | GRB2 (0.41) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL7899915 | 0.91 | GRB2 (0.41) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29706282 | 0.89 | DPP4 (0.42) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL15481300 | 0.89 | DPP4 (0.42) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL29397226 | 0.88 | DPP4 (0.44) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL30937369 | 0.87 | REN (0.43) | GRB2ACEREN | |
| SCHEMBL29591671 | 0.86 | GRB2 (0.44) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615436-A | Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide | 中国医学科学院药物研究所 | 2023-08-18 | — | — | CN | disclosed |