SCHEMBL29397117

SCHEMBL29397117

O=C(O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 7/20 0.46
▸ DPP8 Q6V1X1 2/20 0.46
▸ FAP Q12884 1/20 0.46
▸ DPP9 Q86TI2 1/20 0.46
▸ DPP7 Q9UHL4 1/20 0.46
▸ ANPEP P15144 1/20 0.39
▸ CAPN1 P07384 3/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ CTSB P07858 1/20 0.38
▸ ITGB1 P05556 1/20 0.37
▸ ITGA4 P13612 1/20 0.37
▸ PLG P00747 1/20 0.37
▸ PLAT P00750 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397226 0.98 DPP4 (0.44) DPP4DPP8FAPDPP9DPP7
SCHEMBL2184762 0.89 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL2194423 0.89 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL29408003 0.89 DPP4 (0.45) DPP4DPP8FAPDPP9DPP7
SCHEMBL21519838 0.89 CAPN1 (0.48) DPP4DPP8FAPDPP9DPP7
SCHEMBL30445980 0.88 CAPN1 (0.41) DPP7CAPN1KMT2AMEN1CTSB
SCHEMBL29658175 0.88 CAPN1 (0.42) DPP4DPP8FAPDPP9DPP7
SCHEMBL29616517 0.87 CAPN1 (0.51) DPP4DPP8FAPDPP9DPP7
SCHEMBL29438447 0.87 DPP4 (0.43) DPP4DPP8FAPDPP9DPP7
SCHEMBL30051232 0.87 KMT2A (0.51) DPP4DPP8FAPDPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978100-A Tizepa Process for producing peptide 四川吉晟生物医药有限公司 2025-05-13 — — CN claimed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 — — EP claimed
US-20240209056-A1 GIP AND GLP-1 DUAL RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION, AND USE BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2024-06-27 — — US claimed
WO-2023031455-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS SANOFI SA (FR) 2023-03-09 — — WO claimed
US-20220168396-A1 MULTI-RECEPTOR AGONIST AND MEDICAL USE THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2022-06-02 — — US claimed
EP-4593864-A1 METHODS FOR TREATING OBESITY Zealand Pharma A/S (DK) 2025-08-06 — — EP disclosed
CN-119978100-A Tizepa Process for producing peptide 四川吉晟生物医药有限公司 2025-05-13 — — CN disclosed
CN-118791589-A Polypeptide synthesis method with long chain side chain 甘肃瑞德林生物有限公司 2024-10-18 — — CN disclosed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 — — EP disclosed
US-20240209056-A1 GIP AND GLP-1 DUAL RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION, AND USE BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2024-06-27 — — US disclosed
US-20240174728-A1 A USE OF A POLYPEPTIDE COMPOUND IN THE PREPARATION OF DRUGS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND RELATED INTESTINAL FIBROSIS SHENZHEN TURIER BIOTECH CO., LTD. (CN) 2024-05-30 — — US disclosed
WO-2024068848-A1 METHODS FOR TREATING OBESITY ZEALAND PHARMA A/S (DK) 2024-04-04 — — WO disclosed
EP-4196495-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP Pharma GmbH (CH) 2023-06-21 — — EP disclosed
CN-116171164-A GLP-1/GIP dual agonists 太阳医药工业有限公司 2023-05-26 — — CN disclosed
WO-2023031455-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS SANOFI SA (FR) 2023-03-09 — — WO disclosed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN disclosed
WO-2022156189-A1 USE OF POLYPEPTIDE COMPOUND IN PREVENTION OR TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INTESTINAL FIBROSIS RELATED THERETO 深圳市图微安创科技开发有限公司 2022-07-28 — — WO disclosed
US-20220168396-A1 MULTI-RECEPTOR AGONIST AND MEDICAL USE THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2022-06-02 — — US disclosed
WO-2022034062-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP PHARMA AG (CH) 2022-02-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174728-A1 A USE OF A POLYPEPTIDE COMPOUND IN THE PREPARATION OF DRUGS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND RELATED INTESTINAL FIBROSIS VIP, FN1, COL14A1 DPP4 1561/4885DPP8 1587/4885FAP 101/4885
US-20220168396-A1 MULTI-RECEPTOR AGONIST AND MEDICAL USE THEREOF GLP1R, GIPR, GCGR DPP4 41/4885DPP8 76/4885FAP 2088/4885
US-20240209056-A1 GIP AND GLP-1 DUAL RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION, AND USE GIPR, GLP1R, GCGR DPP4 60/4885DPP8 73/4885FAP 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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