Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisphenol A SCHEMBL28886001 | 0.92 | ESR1 (0.47) | ESR1TSHRESR2CYP3A4ESRRG | |
| 4-Aminophenol SCHEMBL27610995 | 0.83 | TSHR (0.45) | ESR1TSHRESR2CYP3A4SLC6A2 | |
| Bisphenol A SCHEMBL3081593 | 0.82 | ESR1 (0.50) | ESR1TSHRESR2CYP3A4ESRRG | |
| Bisphenol A SCHEMBL29194979 | 0.82 | ESR1 (0.44) | ESR1TSHRESR2CYP3A4ESRRG | |
| SCHEMBL5229243 | 0.82 | POLB (0.51) | ESR1TSHRESR2CYP3A4ESRRG | |
| Phenol SCHEMBL3097293 | 0.81 | POLB (0.56) | ESR1ESR2CYP3A4POLBHTT | |
| SCHEMBL346370 | 0.80 | POLB (0.62) | TSHRPOLBHTTAPEX1TDP1 | |
| SCHEMBL29981767 | 0.79 | HTT (0.68) | TSHRPOLBHTTAPEX1TDP1 | |
| SCHEMBL31265922 | 0.79 | HTT (0.68) | TSHRPOLBHTTAPEX1TDP1 | |
| SCHEMBL15084281 | 0.79 | HTT (0.68) | TSHRPOLBHTTAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341972-A1 | POROUS COMPOSITE BIOMATERIALS AND RELATED METHODS | HAPPE SPINE, LLC (US) | 2024-10-17 | — | — | US | disclosed |
| US-12048633-B2 | Porous composite biomaterials and related methods | HAPPE SPINE, LLC (US) | 2024-07-30 | — | — | US | disclosed |
| US-20220062004-A1 | POROUS COMPOSITE BIOMATERIALS AND RELATED METHODS | HAPPE SPINE, LLC (US) | 2022-03-03 | — | — | US | disclosed |