Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623776 | 0.96 | POLB (0.58) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL7631164 | 0.96 | POLB (0.58) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL31265922 | 0.96 | HTT (0.68) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL15084281 | 0.96 | HTT (0.68) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL29981767 | 0.96 | HTT (0.68) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL3174130 | 0.95 | POLB (0.60) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL7630198 | 0.93 | POLB (0.55) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL14173142 | 0.93 | POLB (0.56) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL59813 | 0.93 | POLB (0.56) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL19270344 | 0.92 | POLB (0.54) | POLBHTTTDP1APEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | IVOCLAR VIVADENT AG (LI) | 2026-05-14 | — | — | US | claimed |
| US-12514791-B2 | Aesthetic dental filling material having high curing depth | IVOCLAR VIVADENT AG (LI) | 2026-01-06 | — | — | US | claimed |
| US-20250352435-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | IVOCLAR VIVADENT AG (LI) | 2025-11-20 | — | — | US | claimed |
| EP-4591847-A1 | 2-COMPONENT DENTAL MATERIALS BASED ON CROSSLINKED POLYMERIC PARTICLES BEARING ACYLTHIOUREA GROUPS | Ivoclar Vivadent AG (LI) | 2025-07-30 | — | — | EP | claimed |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | IVOCLAR VIVADENT AG (LI) | 2025-01-16 | — | — | US | claimed |
| EP-4488243-A1 | ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2025-01-08 | — | — | EP | claimed |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2024-09-10 | — | — | US | claimed |
| EP-4414390-A1 | ACYLTHIOUREA OLIGOMERS SUITABLE AS REDOX INITIATOR COMPONENTS AND RADICALLY POLYMERIZABLE COMPOSITIONS COMPRISING THEM | Ivoclar Vivadent AG (LI) | 2024-08-14 | — | — | EP | claimed |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2024-07-23 | — | — | US | claimed |
| US-20240198582-A1 | HYBRID RESIN COMPOSITION FOR THE 3D-PRINTING OF OBJECTS | CUBICURE GMBH (AT) | 2024-06-20 | — | — | US | claimed |
| EP-0984053-B1 | PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORP (JP) | 2006-09-06 | — | — | EP | claimed |
| WO-2006059984-A1 | MODIFIED POROUS MATERIALS AND METHOD OF FORMING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-06-08 | — | — | WO | claimed |
| US-20060115644-A1 | Modified porous materials and method of forming the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-06-01 | — | — | US | claimed |
| US-6979702-B1 | Ionomer composite compositions | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-12-27 | — | — | US | claimed |
| WO-2000055253-A1 | IONOMER COMPOSITE COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-09-21 | — | — | WO | claimed |
| US-5364890-A | (meth)acrylate and a carbodiimide | GC CORPORATION (JP) | 1994-11-15 | — | — | US | claimed |
| US-5321053-A | Curable mixture of vinyl monomer containing acidic group and photoinitiator | KURARAY CO., LTD. (JP) | 1994-06-14 | — | — | US | claimed |
| EP-0012948-B1 | SCRATCH-RESISTANT, DYEABLE COATING COMPOSITIONS FOR SYNTHETIC RESIN ARTICLES | MITSUBISHI RAYON CO., LTD. (JP) | 1983-02-02 | — | — | EP | claimed |
| US-4291097-A | PHOTOPOLYMERIZATION OF AN ACRYLIC ESTER MIXTURE WITH PHOSPHORIC ACID ESTER AND AN ETHANOLAMINE | MITSUBISHI RAYON CO., LTD. (JP) | 1981-09-22 | — | — | US | claimed |
| EP-0012948-A1 | Scratch-resistant, dyeable coating compositions for synthetic resin articles | MITSUBISHI RAYON CO., LTD. (JP) | 1980-07-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | HBG1, TCP1, GSTM1 | POLB 1375/4885HTT 802/4885TDP1 1134/4885 |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | TAS2R10, PAM, HBG1 | POLB 697/4885HTT 574/4885TDP1 1369/4885 |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | CBR3, NR1H3, NR1I3 | POLB 1217/4885HTT 2557/4885TDP1 4425/4885 |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | HAO2, HAO1, CDH1 | POLB 2973/4885HTT 2078/4885TDP1 3608/4885 |
| US-20250352435-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | CAD, REV1, RAD51 | POLB 649/4885HTT 565/4885TDP1 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.