Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718255 | 1.00 | MMP1 (0.40) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL24496140 | 0.87 | CCR6 (0.38) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL29438915 | 0.87 | TEAD1 (0.49) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL22718251 | 0.87 | TEAD1 (0.49) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL29438917 | 0.87 | TEAD1 (0.49) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL24496004 | 0.86 | BMP1 (0.39) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL24496286 | 0.86 | CCR6 (0.38) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL29648328 | 0.86 | CCR6 (0.38) | MMP1MMP9MMP13CCR6MDM2 | |
| SCHEMBL22843482 | 0.86 | CCR6 (0.43) | CCR6KDM4EMAPTMEN1KMT2A | |
| SCHEMBL22718153 | 0.86 | MMP1 (0.40) | MMP1MMP9MMP13CCR6MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3976194-A2 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |