Xanthochymol

Xanthochymol

SCHEMBL294395

C=C(C)CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(=C)C

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 9/20 0.63
▸ HDAC11 Q96DB2 2/20 0.63
▸ KAT2B Q92831 2/20 0.63
▸ PTGES O14684 1/20 0.63
▸ HDAC8 Q9BY41 1/20 0.63
▸ POLL Q9UGP5 7/20 0.47
▸ STAT1 P42224 1/20 0.46
▸ MET P08581 3/20 0.45
▸ SIRT2 Q8IXJ6 3/20 0.43
▸ SIRT1 Q96EB6 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthochymol SCHEMBL18176145 1.00 EP300 (0.63) EP300HDAC11KAT2BPTGESHDAC8
Xanthochymol SCHEMBL14867275 1.00 EP300 (0.63) EP300HDAC11KAT2BPTGESHDAC8
Isogarcimultiflorone F SCHEMBL31345865 1.00 EP300 (0.63) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL23815733 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL25049796 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL23815760 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Garcinol SCHEMBL294532 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL23815758 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL23607580 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8
Guttiferone F SCHEMBL19565392 0.92 EP300 (0.75) EP300HDAC11KAT2BPTGESHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 — — WO claimed
CN-111743883-A Benzophenone derivative composition, preparation method and application thereof 中南民族大学 2020-10-09 — — CN claimed
CN-109020945-A A kind of different gamboge amphyl, preparation method and application 贵州省中国科学院天然产物化学重点实验室 2018-12-18 — — CN claimed
CN-104274831-A Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound SOO TUCK POOI 2015-01-14 — — CN claimed
US-8329743-B2 Compositions and its use in treating obesity or inducing weight loss SAMI LABS LIMITED (IN) 2012-12-11 — — US claimed
US-20120178801-A1 COMPOSITIONS AND ITS USE IN TREATING OBESITY OR INDUCING WEIGHT LOSS SAMI LABS LIMITED (IN) 2012-07-12 — — US claimed
JP-11139965-A — — None — — JP disclosed
US-12447188-B2 Compositions and methods for the antiseptic treatment of biofilms on mammalian tissue AVADIM HOLDINGS, INC. (US) 2025-10-21 — — US disclosed
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 — — WO disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
US-20240269106-A1 SMALL MOLECULE MODULATOR TARGETING A RARE HISTONE MODIFICATION REGULATING ADIPOGENESIS AND PHARMACEUTICAL FORMULATION THEREOF COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) 2024-08-15 — — US disclosed
EP-4346786-A1 SMALL MOLECULE MODULATOR TARGETING A RARE HISTONE MODIFICATION REGULATING ADIPOGENESIS AND PHARMACEUTICAL FORMULATION THEREOF Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2024-04-10 — — EP disclosed
WO-2022254465-A1 SMALL MOLECULE MODULATOR TARGETING A RARE HISTONE MODIFICATION REGULATING ADIPOGENESIS AND PHARMACEUTICAL FORMULATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2022-12-08 — — WO disclosed
EP-2070543-A1 High-efficiency procedure for preparing standarized hydroalcoholic propolis extract Bios Line S.p.a. (IT) 2009-06-17 — — EP disclosed
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 — — EP disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 — — WO disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 — — US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 — — EP disclosed
US-5972357-A CONTAINING POLYISOPRENYLATED BENZOPHENONE DERIVATIVES AS EFFECTIVE INGREDIENTS AND HAVING A VARIETY OF FUNCTIONS FOR MAINTAINING HEALTH SUCH AS ANTI-ULCER ACTIVITY, THE MAILLARD REACTION INHIBITING ACTIVITY, ANTI-OXIDATION ACTIVITY, OXYGEN KIKKOMAN CORPORATION (JP) 1999-10-26 — — US disclosed
JP-H11139965-A ANTITUMOR AGENT KIKKOMAN CORP 1999-05-25 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC EP300 1222/4885HDAC11 626/4885KAT2B 876/4885
US-20240269106-A1 SMALL MOLECULE MODULATOR TARGETING A RARE HISTONE MODIFICATION REGULATING ADIPOGENESIS AND PHARMACEUTICAL FORMULATION THEREOF EP300, HDAC1, HDAC3 EP300 1/4885HDAC11 5/4885KAT2B 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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