Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981441 | 1.00 | GAA (0.55) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL11981401 | 0.81 | GAA (0.48) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL18025752 | 0.76 | IDO1 (0.51) | ALDH1A1MAPTIDO1PDE4D | |
| SCHEMBL9374643 | 0.75 | IDO1 (0.59) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL9373660 | 0.75 | IDO1 (0.59) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL9374648 | 0.75 | IDO1 (0.59) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL9373669 | 0.75 | IDO1 (0.59) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL3264451 | 0.73 | ALDH1A1 (0.69) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL27791302 | 0.73 | HTR2C (0.56) | GAAALDH1A1MAPTIDO1LMNA | |
| SCHEMBL27727009 | 0.72 | IDO1 (0.52) | GAAALDH1A1MAPTIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531853-A2 | HARNESSING IKZF:BETA-CATENIN COMPLEXES IN THE TREATMENT OF LYMPHOCYTE ASSOCIATED DISEASES OR CONDITIONS | Yale University (US) | 2025-04-09 | — | — | EP | claimed |
| WO-2023230507-A2 | HARNESSING IKZF:BETA-CATENIN COMPLEXES IN THE TREATMENT OF LYMPHOCYTE ASSOCIATED DISEASES OR CONDITIONS | YALE UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| CN-115569541-A | Preparation method of tetrazolyl self-polymerized microporous polymer/graphene oxide mixed matrix membrane | 长春工业大学 | 2023-01-06 | — | — | CN | claimed |
| CN-112915810-B | Pollution-resistant oxygen-permeable film material and preparation method thereof | 浙江高远新材料科技有限公司 | 2023-01-06 | — | — | CN | claimed |
| US-12638439-B2 | Method of using human spheroids for drug discovery | AXOSIM, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4531853-A2 | HARNESSING IKZF:BETA-CATENIN COMPLEXES IN THE TREATMENT OF LYMPHOCYTE ASSOCIATED DISEASES OR CONDITIONS | Yale University (US) | 2025-04-09 | — | — | EP | disclosed |
| EP-3460863-B1 | COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO LTD (KR) | 2024-04-24 | — | — | EP | disclosed |
| WO-2023230507-A2 | HARNESSING IKZF:BETA-CATENIN COMPLEXES IN THE TREATMENT OF LYMPHOCYTE ASSOCIATED DISEASES OR CONDITIONS | YALE UNIVERSITY (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20230228740-A1 | METHOD OF USING HUMAN SPHEROIDS FOR DRUG DISCOVERY | StemoniX Inc. (US) | 2023-07-20 | — | — | US | disclosed |
| CN-109516992-B | Nitrogen-containing compound and organic electroluminescent device comprising same | 三星显示有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112915810-B | Pollution-resistant oxygen-permeable film material and preparation method thereof | 浙江高远新材料科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-109010916-B | Moldable formulations containing oxysterol in acellular tissue matrices | 华沙整形外科股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638439-B2 | Method of using human spheroids for drug discovery | CACNA1E, PDE1B, ORAI1 | GAA 4798/4885ALDH1A1 520/4885MAPT 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.