Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.33 |
| ▸ | DRD3 | P35462 | 6/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15903582 | 1.00 | HTR2A (0.33) | HTR2ADRD3DRD2SLC6A4HTR7 | |
| SCHEMBL17279076 | 0.85 | DRD2 (0.31) | HTR2ADRD3DRD2SLC6A4HTR7 | |
| SCHEMBL15903440 | 0.81 | CYP17A1 (0.34) | HTR2ADRD3DRD2SLC6A4HTR7 | |
| SCHEMBL15904097 | 0.79 | HTR2A (0.35) | HTR2ADRD3HTR7 | |
| SCHEMBL29440842 | 0.79 | CYP17A1 (0.35) | — | |
| SCHEMBL15903651 | 0.79 | CYP17A1 (0.35) | — | |
| SCHEMBL17272910 | 0.78 | RET (0.31) | HTR2AHTR7 | |
| SCHEMBL32680153 | 0.77 | RET (0.32) | HTR2AHTR7 | |
| SCHEMBL22304321 | 0.75 | ACHE (0.30) | — | |
| SCHEMBL17279077 | 0.75 | RET (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045653-A | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111135171-B | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114085236-A | Aldehyde conjugates and uses thereof | 奥尔德拉医疗公司 | 2022-02-25 | — | — | CN | disclosed |