SCHEMBL29440907

SCHEMBL29440907

CC1=CC(=O)c2cccc(O)c2C1=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.74
KMT2A Q03164 6/20 0.74
ALDH1A1 P00352 6/20 0.74
MAPK1 P28482 6/20 0.74
KDM4E B2RXH2 6/20 0.74
RECQL P46063 6/20 0.74
MEN1 O00255 5/20 0.74
BLM P54132 4/20 0.74
HPGD P15428 4/20 0.74
TDP1 Q9NUW8 4/20 0.74
CYP3A4 P08684 4/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
ALOX15 P16050 3/20 0.74
HSD17B10 Q99714 3/20 0.74
TP53 P04637 3/20 0.74
CDC25B P30305 3/20 0.74
CYP1A2 P05177 2/20 0.74
HSPD1 P10809 2/20 0.74
CDC25A P30304 2/20 0.74
HSPE1 P61604 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4304001 1.00 MAPT (0.74) MAPTKMT2AALDH1A1MAPK1KDM4E
Plumbagin SCHEMBL29386213 0.85 MAPT (1.00) MAPTKMT2AALDH1A1MAPK1KDM4E
Plumbagin SCHEMBL34186 0.85 MAPT (1.00) MAPTKMT2AALDH1A1MAPK1KDM4E
Plumbagin SCHEMBL27811730 0.84 MAPT (0.96) MAPTKMT2AALDH1A1MAPK1KDM4E
Plumbagin SCHEMBL14246176 0.82 MAPT (0.84) MAPTKMT2AALDH1A1MAPK1KDM4E
SCHEMBL29906401 0.81 ALDH1A1 (0.59) MAPTKMT2AALDH1A1MAPK1KDM4E
SCHEMBL29728494 0.81 MAPT (0.72) MAPTKMT2AALDH1A1MAPK1KDM4E
SCHEMBL5175867 0.81 MAPT (0.72) MAPTKMT2AALDH1A1MAPK1KDM4E
SCHEMBL5811709 0.81 ALDH1A1 (0.59) MAPTKMT2AALDH1A1MAPK1KDM4E
Plumbagin SCHEMBL2720467 0.80 MAPT (0.87) MAPTKMT2AALDH1A1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116194204-A Ceramic coating for reducing deposition of metallic transition metals on metal parts in hydrogenation reactions 帝斯曼知识产权资产管理有限公司 2023-05-30 CN disclosed
WO-2022058576-A1 CERAMIC COATING ON METAL PARTS TO REDUCE DEPOSIT OF METALLIC TRANSITION METALS IN HYDROGENATION REACTIONS DSM IP ASSETS B.V. (NL) 2022-03-24 WO disclosed
CN-109498469-B Walnut green seedcase hair blackening sunscreen spray and preparation method and application thereof 山东师范大学 2022-02-08 CN disclosed