Plumbagin

Plumbagin

SCHEMBL34186

CC1=CC(=O)c2c(O)cccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 1.00
ALDH1A1 P00352 7/20 1.00
KMT2A Q03164 7/20 1.00
MAPK1 P28482 6/20 1.00
KDM4E B2RXH2 6/20 1.00
RECQL P46063 6/20 1.00
MEN1 O00255 6/20 1.00
BLM P54132 4/20 1.00
HPGD P15428 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
CYP3A4 P08684 4/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
ALOX15 P16050 3/20 1.00
HSD17B10 Q99714 3/20 1.00
TP53 P04637 3/20 1.00
CDC25B P30305 3/20 1.00
CYP1A2 P05177 2/20 1.00
HSPD1 P10809 2/20 1.00
CDC25A P30304 2/20 1.00
HSPE1 P61604 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Plumbagin SCHEMBL29386213 1.00 MAPT (1.00) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL27811730 0.98 MAPT (0.96) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL28589491 0.93 MAPT (0.87) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL2720467 0.93 MAPT (0.87) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL3427829 0.92 MAPT (0.84) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL14246176 0.92 MAPT (0.84) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL28261630 0.89 MAPT (0.79) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL28434705 0.88 MAPT (0.77) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL28016669 0.87 MAPT (0.75) MAPTALDH1A1KMT2AMAPK1KDM4E
Plumbagin SCHEMBL28260327 0.85 MAPT (0.73) MAPTALDH1A1KMT2AMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7177 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
CN-122012305-A Pseudomonas putida (Pseudomonas putida) RT12 and application thereof 新疆林科院经济林研究所 2026-05-12 CN claimed
CN-117753479-B Photocatalyst of carbon-nitrogen coated transition metal cluster, and preparation method and application thereof 中国石油大学(北京) 2026-05-12 CN claimed
US-12616659-B2 Therapeutic agent nanoparticles and methods of preparation NANO PHARMASOLUTIONS, INC. (US) 2026-05-05 US claimed
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
US-20260061091-A1 MUSSEL-INSPIRED TISSUE ADHESIVES AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US claimed
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250387443-A1 ENHANCING ONCOLYTIC VIROTHERAPY WITH A COMBINATION OF NUCLEAR EXPORT INHIBITOR AND MYXOMA VIRUS ACTIVATING CELL DEATH PATHWAYS UNIV ARIZONA STATE (US) 2025-12-25 US claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
WO-1992000748-A1 POLY(ALKYLENE OXIDE) AMINO ACID COPOLYMERS AND DRUG CARRIERS AND CHARGED COPOLYMERS BASED THEREON ENZON, INC. (US) 1992-01-23 WO claimed
US-4895575-A HAIR DYES L'OREAL (FR) 1990-01-23 US claimed
US-4620850-A HYDROXYBENZOLFURANONE WELLA AKTIENGESELLSCHAFT (DE) 1986-11-04 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0152852-A2 Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs PÜHRINGER, Josef, Dr. (SE) 1985-08-28 EP claimed
EP-0124393-A1 Hair dyeing composition and process ALBAN MULLER INTERNATIONAL, S.A.R.L. (FR) 1984-11-07 EP claimed
EP-0026473-B1 OXIDATIVE HAIR-DYEING COMPOSITION Wella Aktiengesellschaft (DE) 1983-05-25 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4283342-A REACTION PRODUCT OF A HYDROXYQUINONE AND A CIS-PLATINUM COMPOUND UNIVERSITY OF DELAWARE (US) 1981-08-11 US claimed