Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28993006 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL10353528 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL20061313 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL14726516 | 0.93 | ITGB1 (0.42) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL14726541 | 0.92 | ITGB1 (0.42) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL14726434 | 0.91 | GAA (0.44) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL14726514 | 0.90 | ITGB1 (0.44) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL9884059 | 0.89 | LMNA (0.43) | ITGB1ITGA4MAPTNPSR1ITGA2 | |
| SCHEMBL14726518 | 0.89 | TAS1R3 (0.54) | ITGB1ITGA4MAPTGAARAB9A | |
| SCHEMBL14726648 | 0.89 | KAT6A (0.41) | ITGB1ITGA4MAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873000-B | Isoquinolinones and quinazolinones compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115873000-A | Isoquinolone and quinazolinone compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-109071462-B | Quinazoline derivative or salt thereof and pharmaceutical composition containing the same | 柳韩洋行 | 2022-02-08 | — | — | CN | disclosed |