SCHEMBL2944198

SCHEMBL2944198

COc1ccc(-c2c3c(F)c(F)c(F)c(F)c3c(-c3ccc(F)c(F)c3)c3c(F)c(F)c(F)c(F)c23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
POLB P06746 1/20 0.46
STAT3 P40763 1/20 0.42
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
RPS6KA3 P51812 1/20 0.38
APP P05067 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
USP2 O75604 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2727043 0.90 L3MBTL1 (0.46) L3MBTL1POLBSTAT3MEN1KMT2A
SCHEMBL2725454 0.88 ANPEP (0.40) L3MBTL1POLBCYP11B1CYP11B2RPS6KA3
SCHEMBL12086227 0.88 L3MBTL1 (0.40) L3MBTL1POLBSTAT3CYP2C19MEN1
SCHEMBL2731490 0.88 L3MBTL1 (0.40) L3MBTL1POLBSTAT3CYP2C19MEN1
SCHEMBL2938302 0.87 L3MBTL1 (0.39) L3MBTL1POLBSTAT3CYP11B1CYP11B2
SCHEMBL12086091 0.86 MEN1 (0.42) L3MBTL1POLBSTAT3MEN1KMT2A
SCHEMBL2712297 0.86 MEN1 (0.42) L3MBTL1POLBSTAT3MEN1KMT2A
SCHEMBL2724736 0.84 NOTUM (0.39) CYP11B1CYP11B2CYP2C19CYP1A2ALDH1A1
SCHEMBL2727618 0.83 PTGS2 (0.40) CYP1A2NPC1TP53MAPK1CASP3
SCHEMBL2725027 0.83 NPC1 (0.37) CYP11B1CYP11B2APPNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 L3MBTL1 2477/4885POLB 3331/4885STAT3 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.