Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.54 |
| ▸ | NPY1R | P25929 | 3/20 | 0.54 |
| ▸ | NPY4R | P50391 | 3/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442113 | 0.94 | EPHA2 (0.58) | EPHA2NPY5RNPY1RNPY4RNMUR2 | |
| SCHEMBL29442118 | 0.87 | EPHA2 (0.57) | EPHA2NPY5RNPY1RNPY4ROPRM1 | |
| SCHEMBL29442099 | 0.85 | OPRD1 (0.59) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL34470213 | 0.81 | C5AR1 (0.60) | EPHA2NPY5RNPY1RNPY4RNPY2R | |
| SCHEMBL26454899 | 0.80 | NMUR2 (0.57) | EPHA2NPY5RNPY1RNPY4RNMUR2 | |
| SCHEMBL13402619 | 0.80 | OPRM1 (0.58) | EPHA2NPY1RNMUR2NMUR1OPRM1 | |
| SCHEMBL30050976 | 0.80 | OPRD1 (0.63) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL30892660 | 0.80 | EPHA2 (0.58) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL11333637 | 0.79 | OPRM1 (0.64) | EPHA2NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL19780502 | 0.79 | C5AR1 (0.54) | EPHA2NMUR2NMUR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096656-A1 | NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS | NORTHWESTERN UNIVERSITY | 2022-03-31 | — | — | US | disclosed |