Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28534473 | 1.00 | TRPV1 (0.45) | TRPV1FFAR1P4HTMKCNQ3KCNQ2 | |
| SCHEMBL29442878 | 0.93 | KCNQ3 (0.46) | TRPV1FFAR1P4HTMKCNQ3KCNQ2 | |
| SCHEMBL21394709 | 0.93 | KCNQ3 (0.46) | TRPV1FFAR1P4HTMKCNQ3KCNQ2 | |
| SCHEMBL28534471 | 0.85 | SGMS2 (0.42) | TRPV1FFAR1P4HTMKCNQ3KCNQ2 | |
| SCHEMBL21395237 | 0.84 | SNCA (0.48) | FFAR1P4HTMKCNQ3KCNQ2KCNE1 | |
| SCHEMBL29442785 | 0.84 | SNCA (0.48) | FFAR1P4HTMKCNQ3KCNQ2KCNE1 | |
| Trifluoroacetic Acid SCHEMBL30862015 | 0.79 | MLLT1 (0.51) | FFAR1P4HTMSLC2A1HIF1ASNCA | |
| SCHEMBL21394767 | 0.75 | ALDH1A1 (0.47) | P4HTMHIF1ASNCAHDAC3HDAC1 | |
| SCHEMBL29358525 | 0.75 | ALDH1A1 (0.47) | P4HTMHIF1ASNCAHDAC3HDAC1 | |
| SCHEMBL21394466 | 0.75 | ALDH1A1 (0.48) | P4HTMHDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |