Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395237 | 0.80 | SNCA (0.48) | SGMS2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29442785 | 0.80 | SNCA (0.48) | SGMS2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29442876 | 0.74 | NR3C2 (0.44) | MEN1KMT2ANR3C2 | |
| SCHEMBL30862009 | 0.73 | KCNH2 (0.48) | RAB9ANPC1NR3C2 | |
| SCHEMBL28117989 | 0.73 | PARP1 (0.47) | ALDH1A1KDM4EMAPTL3MBTL1NR3C2 | |
| SCHEMBL18160598 | 0.69 | DYRK1A (0.65) | — | |
| SCHEMBL21394908 | 0.69 | RAB9A (0.52) | SGMS2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL21394624 | 0.69 | NPC1 (0.48) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL29358776 | 0.69 | NPC1 (0.48) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL21394709 | 0.68 | KCNQ3 (0.46) | SGMS2KCNQ3KCNQ2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |