Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21852141 | 0.77 | TNKS2 (0.66) | TNKS2METMTNR1AMTNR1BALOX5 | |
| SCHEMBL29699646 | 0.74 | MEN1 (0.41) | TNKS2CSNK2A2CSNK2BCSNK2A1MTNR1A | |
| SCHEMBL3486438 | 0.74 | MEN1 (0.41) | TNKS2CSNK2A2CSNK2BCSNK2A1MTNR1A | |
| SCHEMBL1976272 | 0.73 | MEN1 (0.53) | ALOX5ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL1973909 | 0.73 | MEN1 (0.53) | ALOX5ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL18225869 | 0.71 | ACHE (0.61) | TNKS2ACHEALDH1A1KDM4EMEN1 | |
| SCHEMBL8169870 | 0.71 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1ALOX5ALDH1A1 | |
| SCHEMBL7197872 | 0.70 | XDH (0.56) | CSNK2A2CSNK2BCSNK2A1ALOX5ALDH1A1 | |
| SCHEMBL7197568 | 0.70 | ESR1 (0.45) | CSNK2A2CSNK2BCSNK2A1ALOX5ALDH1A1 | |
| SCHEMBL7197558 | 0.70 | ESR1 (0.45) | CSNK2A2CSNK2BCSNK2A1ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114184727-B | Identification method of three medicinal materials from gleditsia sinensis and application thereof | 天津中医药大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114184727-A | Identification method of three medicinal materials derived from gleditschia horrida and application thereof | 天津中医药大学 | 2022-03-15 | — | — | CN | disclosed |