SCHEMBL29444063

SCHEMBL29444063

N#Cc1ccc(-c2ccc(OCCCCCCCCCCOc3ccc(-c4ccc(C#N)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.67
HDAC2 Q92769 1/20 0.67
MMP3 P08254 5/20 0.64
MMP2 P08253 5/20 0.64
HRH3 Q9Y5N1 10/20 0.63
HRH2 P25021 8/20 0.63
HRH1 P35367 8/20 0.63
MMP1 P03956 1/20 0.58
MMP9 P14780 1/20 0.58
MMP13 P45452 1/20 0.58
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 2/20 0.58
HTT P42858 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16841044 1.00 HDAC1 (0.67) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL18079151 1.00 HDAC1 (0.67) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL26602050 0.98 MMP3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL7387284 0.94 HRH3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL7983991 0.94 HRH3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL5526919 0.94 HRH3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL12408526 0.94 HRH3 (0.66) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL5519875 0.91 HRH3 (0.62) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL25187982 0.91 KDM4E (0.71) HDAC1HDAC2MMP3MMP2HRH3
SCHEMBL25189699 0.91 KDM4E (0.71) HDAC1HDAC2MMP3MMP2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119612-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2023-04-20 US claimed
EP-3344275-B1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF AILERON THERAPEUTICS INC (US) 2023-03-08 EP claimed
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL FURUKAWA ELECTRIC CO., LTD. (JP) 2026-01-15 US disclosed
US-20230127248-A1 PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF AILERON THERAPEUTICS, INC. 2023-04-27 US disclosed
US-11637566-B2 Storage device and control method for storage device FUJITSU LIMITED (JP) 2023-04-25 US disclosed
US-20230119612-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2023-04-20 US disclosed
US-20230106577-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF AILERON THERAPEUTICS, INC. 2023-04-06 US disclosed
EP-3344275-B1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF AILERON THERAPEUTICS INC (US) 2023-03-08 EP disclosed
US-20230037284-A9 COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2023-02-02 US disclosed
US-20220385304-A1 STORAGE DEVICE AND CONTROL METHOD FOR STORAGE DEVICE FUJITSU LIMITED (JP) 2022-12-01 US disclosed
CN-216552986-U Safety protection structure is used in outdoor decoration construction in high altitude 北京科源顺达建设工程有限公司 2022-05-17 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-216082270-U Cement hardness detection device for highway construction 解延强 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL SEM1, PCNA, RPL34 HDAC1 671/4885HDAC2 1558/4885MMP3 2916/4885
US-20230127248-A1 PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF MDM2, TP53, TP53BP1 HDAC1 2152/4885HDAC2 3610/4885MMP3 3397/4885
US-20230119612-A1 PEPTIDOMIMETIC MACROCYCLES TP53, MDM2, MDM4 HDAC1 2639/4885HDAC2 3981/4885MMP3 3905/4885
US-20230037284-A9 COMBINATION THERAPY OF PEPTIDOMIMETIC MACROCYCLES BID, FLT3, GRPR HDAC1 1893/4885HDAC2 2662/4885MMP3 1419/4885
US-20230106577-A1 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF TP53, TP53BP1, MDM2 HDAC1 560/4885HDAC2 1905/4885MMP3 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.