Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MMP3 | P08254 | 3/20 | 0.57 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | HRH2 | P25021 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12408526 | 0.98 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL5526919 | 0.98 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL7387284 | 0.98 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL7983991 | 0.98 | HRH3 (0.66) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL7384498 | 0.95 | HRH3 (0.59) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL26602050 | 0.93 | MMP3 (0.66) | HRH3ALDH1A1MMP3MMP2HRH2 | |
| SCHEMBL7986752 | 0.92 | ALDH1A1 (0.66) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL20332712 | 0.91 | HRH3 (0.60) | HRH3ALDH1A1MAPTMMP3MMP2 | |
| SCHEMBL18079151 | 0.91 | HDAC1 (0.67) | HRH3ALDH1A1MMP3MMP2HRH2 | |
| SCHEMBL20333565 | 0.91 | HRH3 (0.60) | HRH3ALDH1A1MAPTMMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170345-A1 | THERMALLY STABLE ELASTIC POLYMER-ENCAPSULATED ANODE PARTICLES FOR LITHIUM BATTERIES AND METHOD OF MANUFACTURING | GLOBAL GRAPHENE GROUP, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022170299-A2 | FLAME-RESISTANT QUASI-SOLID AND SOLID-STATE ELECTROLYTES, LITHIUM BATTERIES AND MANUFACTURING METHOD | GLOBAL GRAPHENE GROUP, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-20220246915-A1 | THERMALLY STABLE ELASTIC POLYMER-ENCAPSULATED ANODE PARTICLES FOR LITHIUM BATTERIES AND METHOD OF MANUFACTURING | HONEYCOMB BATTERY COMPANY | 2022-08-04 | — | — | US | disclosed |
| US-20220238914-A1 | FLAME-RESISTANT QUASI-SOLID AND SOLID-STATE ELECTROLYTES, LITHIUM BATTERIES AND MANUFACTURING METHOD | HONEYCOMB BATTERY COMPANY | 2022-07-28 | — | — | US | disclosed |
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
| EP-1572129-A2 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20040147531-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-07-29 | — | — | US | disclosed |
| EP-1420773-A1 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | Neurochem (International) Limited (CH) | 2004-05-26 | — | — | EP | disclosed |
| US-20040006092-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM, INC. (CA) | 2004-01-08 | — | — | US | disclosed |
| WO-2003103598-A2 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2003-12-18 | — | — | WO | disclosed |
| WO-2003017994-A1 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2003-03-06 | — | — | WO | disclosed |
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147531-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, HTT | HRH3 1222/4885ALDH1A1 2054/4885MAPT 11/4885 |
| US-20040006092-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, HTT | HRH3 1222/4885ALDH1A1 2054/4885MAPT 11/4885 |
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, GRN | HRH3 1160/4885ALDH1A1 2283/4885MAPT 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.