Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168542 | 1.00 | RAB9A (0.35) | RAB9APOLBSMN1; SMN2TDP1TSHR | |
| SCHEMBL10790770 | 1.00 | RAB9A (0.35) | RAB9APOLBSMN1; SMN2TDP1TSHR | |
| SCHEMBL10759407 | 0.92 | RAB9A (0.35) | RAB9APOLBSMN1; SMN2TDP1HTT | |
| SCHEMBL10493918 | 0.85 | ALDH1A1 (0.37) | RAB9APOLBSMN1; SMN2HTTHTR2A | |
| SCHEMBL9159892 | 0.84 | ALDH1A1 (0.33) | POLBSMN1; SMN2HTTHTR2A | |
| SCHEMBL9670137 | 0.83 | ALDH1A1 (0.39) | RAB9APOLBSMN1; SMN2TDP1HTT | |
| SCHEMBL10787318 | 0.83 | ALDH1A1 (0.32) | POLBSMN1; SMN2HTTHTR2A | |
| SCHEMBL10563443 | 0.82 | ALDH1A1 (0.34) | POLBSMN1; SMN2HTTHTR2A | |
| SCHEMBL10556308 | 0.82 | HTR2A (0.39) | RAB9APOLBSMN1; SMN2HTTHTR2A | |
| SCHEMBL11096936 | 0.82 | HTR2A (0.39) | RAB9APOLBSMN1; SMN2HTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670806-B9 | PROCESS FOR PREPARATION OF ESTERS OF 2-DIAZO-3-TRIMETHYLSILYLOXY-3-BUTENOIC ACID | RANBAXY LAB LTD (IN) | 2010-06-02 | — | — | EP | disclosed |
| EP-1670806-B1 | PROCESS FOR PREPARATION OF ESTERS OF 2-DIAZO-3-TRIMETHYLSILYLOXY-3-BUTENOIC ACID | RANBAXY LAB LTD (IN) | 2010-01-06 | — | — | EP | disclosed |
| US-4683296-A | ANTIBIOTICS, SILATION | BRISTOL-MYERS COMPANY (US) | 1987-07-28 | — | — | US | disclosed |