Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668098 | 0.81 | POLB (0.46) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL3668622 | 0.79 | OPRL1 (0.53) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL29444535 | 0.78 | POLB (0.43) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL6422849 | 0.78 | SIGMAR1 (0.57) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL19235363 | 0.77 | OPRM1 (0.46) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL6520201 | 0.76 | CYP2D6 (0.42) | MEN1KMT2AL3MBTL1POLBGAA | |
| Hydrochloric Acid SCHEMBL3667689 | 0.76 | POLB (0.44) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL3722396 | 0.76 | MAPT (0.39) | MEN1KMT2AL3MBTL1SIGMAR1TSHR | |
| SCHEMBL3722398 | 0.76 | MAPT (0.39) | MEN1KMT2AL3MBTL1SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL6521624 | 0.75 | POLB (0.43) | MEN1KMT2AL3MBTL1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884096-B | Spiroindolinones as DDR1 inhibitors | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | disclosed |