Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24277215 | 1.00 | TP53 (0.50) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24276927 | 0.91 | TP53 (0.49) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL27118351 | 0.88 | LMNA (0.41) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL29445043 | 0.87 | TP53 (0.53) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24276977 | 0.87 | TP53 (0.53) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24277229 | 0.85 | ABCB1 (0.43) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL30892421 | 0.84 | DYRK1A (0.53) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24277799 | 0.84 | TP53 (0.53) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24276802 | 0.84 | DYRK1A (0.53) | TP53CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL24276869 | 0.83 | MAOA (0.52) | TP53CYP1A2CYP3A4CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4210703-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | Expansion Therapeutics, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022055922-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | EXPANSION THERAPEUTICS, INC. (US) | 2022-03-17 | — | — | WO | disclosed |