Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.52 |
| ▸ | FEN1 | P39748 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936639 | 1.00 | GRM4 (0.53) | GRM4ALOX5APFEN1LRRK2PDE10A | |
| SCHEMBL2404642 | 0.91 | GRM4 (0.54) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL2406994 | 0.91 | GRM4 (0.54) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL2404646 | 0.91 | GRM4 (0.54) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL31702258 | 0.88 | ALOX5AP (0.43) | GRM4ALOX5APFEN1PDE10A | |
| SCHEMBL20687907 | 0.88 | ALOX5AP (0.43) | GRM4ALOX5APFEN1PDE10A | |
| SCHEMBL20240553 | 0.85 | ALOX5AP (0.46) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL4967417 | 0.85 | ALOX5AP (0.46) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL20689295 | 0.83 | GRM4 (0.42) | GRM4ALOX5APFEN1LRRK2 | |
| SCHEMBL9574598 | 0.83 | ALOX5AP (0.47) | GRM4ALOX5APFEN1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848591-B | HDAC inhibitors and methods of making and using the same | 成都先导药物开发股份有限公司 | 2022-03-18 | — | — | CN | disclosed |