SCHEMBL31702258

SCHEMBL31702258

Nc1cccnc1OC1CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 7/20 0.43
FEN1 P39748 7/20 0.43
GRM4 Q14833 3/20 0.41
PDE10A Q9Y233 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20687907 1.00 ALOX5AP (0.43) ALOX5APFEN1GRM4PDE10A
SCHEMBL4967417 0.93 ALOX5AP (0.46) ALOX5APFEN1GRM4
SCHEMBL20240553 0.93 ALOX5AP (0.46) ALOX5APFEN1GRM4
SCHEMBL2369803 0.92 GRM4 (0.40) ALOX5APFEN1GRM4PDE10A
SCHEMBL20689383 0.92 ALOX5AP (0.42) ALOX5APFEN1GRM4PDE10A
Hydrochloric Acid SCHEMBL4714047 0.92 FEN1 (0.50) ALOX5APFEN1GRM4PDE10A
SCHEMBL2379480 0.92 GRM4 (0.40) ALOX5APFEN1GRM4PDE10A
Hydrochloric Acid SCHEMBL4714045 0.92 FEN1 (0.50) ALOX5APFEN1GRM4PDE10A
SCHEMBL9574598 0.91 ALOX5AP (0.47) ALOX5APFEN1GRM4
SCHEMBL29445482 0.88 GRM4 (0.53) ALOX5APFEN1GRM4PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2025-10-16 US disclosed
WO-2025215153-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2025-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS ENPP1, ENPP3, PDE7A ALOX5AP 370/4885FEN1 169/4885GRM4 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.